S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate  纯度: ≥95.0%

S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate 是一种谷胱甘肽可降解 (cleavable) 的 ADC linker,用于抗体偶联药物 (ADCs),属于 Alkyl-Chain 类,是 ADCs 用于 mAb 附着的连接体部分。

S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate

S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate Chemical Structure

CAS No. : 2127875-65-2

规格 价格 是否有货 数量
50 mg ¥4800 In-stock
100 mg ¥6800 In-stock
250 mg ¥9800 In-stock
500 mg   询价  
1 g   询价  

* Please select Quantity before adding items.

生物活性

S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) and refers to the Alkyl-Chain composition. S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is the linker portions of the molecules employed for mAb attachment purposes[1].

IC50 & Target[1]

Cleavable

 

分子量

184.28

Formula

C5H12O3S2

CAS 号

2127875-65-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

参考文献
  • [1]. Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2019 Oct 31.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务