Cas(113775-22-7), (1S,4S)-3-氧代-2-氧杂-5-氮杂双环[2.2.1]庚烷-5-羧酸叔丁酯, N-Boc-4-hydroxy-L-pyrrolidine lactone,Boc-4-hydroxy-L-pyrrolidine lactone,

发表于2026年2月6日由上海金畔生物科技有限公司

(1S,4S)-3-氧代-2-氧杂-5-氮杂双环[2.2.1]庚烷-5-羧酸叔丁酯

95%

有货

CAS编号 113775-22-7 | 品牌：Jinpan

Boc-4-hydroxy-L-pyrrolidine lactone

MSDS

质检证书(CoA)

相似产品

分子式 C₁₀H₁₅NO₄
分子量213.2
MDL号 MFCD06797016
PubChem编号 11252852

货号 (SKU)	包装规格	是否现货
B179549-50mg	50mg	现货
B179549-250mg	250mg	现货
B179549-1g	1g	现货
B179549-5g	5g	现货
B179549-25g	25G	现货

基本信息

产品名称	(1S,4S)-3-氧代-2-氧杂-5-氮杂双环[2.2.1]庚烷-5-羧酸叔丁酯
英文名称	Boc-4-hydroxy-L-pyrrolidine lactone
别名	N-Boc-4-hydroxy-L-pyrrolidine lactone
规格或纯度	95%
运输条件	常规运输

安全信息

WGK	3

CAS编号	113775-22-7
熔点	109-114°C
储存温度	室温
MDL号	MFCD06797016
分子量	213.2
分子式	C₁₀H₁₅NO₄
品牌	Jinpan
PubChem CID	11252852

Cas(113775-22-7), (1S,4S)-3-氧代-2-氧杂-5-氮杂双环[2.2.1]庚烷-5-羧酸叔丁酯, N-Boc-4-hydroxy-L-pyrrolidine lactone,Boc-4-hydroxy-L-pyrrolidine lactone,

发表于2026年2月5日由上海金畔生物科技有限公司

(1S,4S)-3-氧代-2-氧杂-5-氮杂双环[2.2.1]庚烷-5-羧酸叔丁酯

95%

有货

CAS编号 113775-22-7 | 品牌：Jinpan

Boc-4-hydroxy-L-pyrrolidine lactone

MSDS

质检证书(CoA)

相似产品

分子式 C₁₀H₁₅NO₄
分子量213.2
MDL号 MFCD06797016
PubChem编号 11252852

货号 (SKU)	包装规格	是否现货
B179549-50mg	50mg	现货
B179549-250mg	250mg	现货
B179549-1g	1g	现货
B179549-5g	5g	现货
B179549-25g	25G	现货

基本信息

产品名称	(1S,4S)-3-氧代-2-氧杂-5-氮杂双环[2.2.1]庚烷-5-羧酸叔丁酯
英文名称	Boc-4-hydroxy-L-pyrrolidine lactone
别名	N-Boc-4-hydroxy-L-pyrrolidine lactone
规格或纯度	95%
运输条件	常规运输

CAS编号	113775-22-7
熔点	109-114°C
储存温度	室温
MDL号	MFCD06797016
分子量	213.2
分子式	C₁₀H₁₅NO₄
品牌	Jinpan
PubChem CID	11252852

TLR7/8 agonist 4 hydroxy-PEG10-acid

发表于2026年1月1日由上海金畔生物科技有限公司

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

TLR7/8 agonist 4 hydroxy-PEG10-acid

TLR7/8 agonist 4 hydroxy-PEG10-acid (compound 9) 是抗体-药物偶联物的一部分，由 TLR7/8 激活剂 TLR7/8 agonist 4 (HY-139018) 和可降解的 ADC linker hydroxy-PEG10-acid (HY-133307) 连接而成。

TLR7/8 agonist 4 hydroxy-PEG10-acid Chemical Structure

CAS No. : 2388520-17-8

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生物活性

TLR7/8 agonist 4 hydroxy-PEG10-acid (compound 9) is a drug-linker conjugate for ADC with potent antitumor activity by using TLR7/8 agonist 4 (HY-139018; a TLR7/8 agonist), linked via the cleavable ADC linker hydroxy-PEG10-acid (HY-133307)^[1].

IC₅₀ & Target^[1]

Traditional Cytotoxic Agents

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

837.01

Formula

C₄₁H₆₈N₆O₁₂

CAS 号

2388520-17-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Shelley Erin ACKERMAN, et al. Immunoconjugates targeting her2. WO2020190725A1.

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S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate

发表于2025年12月28日由上海金畔生物科技有限公司

S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate 纯度: ≥95.0%

S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate 是一种谷胱甘肽可降解 (cleavable) 的 ADC linker，用于抗体偶联药物 (ADCs)，属于 Alkyl-Chain 类，是 ADCs 用于 mAb 附着的连接体部分。

S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate Chemical Structure

CAS No. : 2127875-65-2

规格	价格	是否有货
50 mg	￥4800	In-stock
100 mg	￥6800	In-stock
250 mg	￥9800	In-stock
500 mg		询价
1 g		询价

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生物活性

S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) and refers to the Alkyl-Chain composition. S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is the linker portions of the molecules employed for mAb attachment purposes^[1].

IC₅₀ & Target^[1]

Cleavable

分子量

184.28

Formula

C₅H₁₂O₃S₂

CAS 号

2127875-65-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

参考文献

[1]. Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2019 Oct 31.

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TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride

发表于2025年12月18日由上海金畔生物科技有限公司

TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride

TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride (compound 9) 是抗体-药物偶联物的一部分，由 TLR7/8 激活剂 TLR7/8 agonist 4 (HY-139018) 和可降解的 ADC linker hydroxy-PEG10-acid (HY-133307) 连接而成。

TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride Chemical Structure

CAS No. : 2388520-36-1

规格		是否有货
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生物活性

TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride (compound 9) is a drug-linker conjugate for ADC with potent antitumor activity by using TLR7/8 agonist 4 (HY-139018; a TLR7/8 agonist), linked via the cleavable ADC linker hydroxy-PEG10-acid (HY-133307)^[1].

IC₅₀ & Target^[1]

Traditional Cytotoxic Agents

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

873.47

Formula

C₄₁H₆₉ClN₆O₁₂

CAS 号

2388520-36-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Shelley Erin ACKERMAN, et al. Immunoconjugates targeting her2. WO2020190725A1.

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Hydroxy-PEG3-(CH2)2-Boc

发表于2025年11月10日由上海金畔生物科技有限公司

Hydroxy-PEG3-(CH2)2-Boc 纯度: ≥95.0%

Hydroxy-PEG2-(CH2)2-Boc 是一种用于合成抗体偶联药物 (ADC) 的 ADC linker，Hydroxy-PEG2-(CH2)2-Boc 源于专利WO2004008101A2 (化合物 196)。Hydroxy-PEG2-(CH2)2-Boc 也可用作 PROTAC linker 用于 PROTAC 的合成。.

Hydroxy-PEG3-(CH2)2-Boc Chemical Structure

CAS No. : 186020-66-6

规格	价格	是否有货
100 mg	￥550	In-stock
200 mg		询价
500 mg		询价

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生物活性

Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196)^[1]. Hydroxy-PEG2-(CH2)2-Boc is also a PROTAC linker that can be used in the synthesis of PROTACs.

IC₅₀ & Target

Non-cleavable

PEGs

Alkyl/ether

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

278.34

Formula

C₁₃H₂₆O₆

CAS 号

186020-66-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

参考文献

[1]. Qingqi Chen,et al. The use of isocyanate linkers to make hydrolyzable active agent biopolymer conjugates. Patent WO2004008101A2.

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5-Hydroxy-7-acetoxyflavone

发表于2025年9月25日由上海金畔生物科技有限公司

5-Hydroxy-7-acetoxyflavone

5-Hydroxy-7-acetoxyflavone 是在各种植物来源中发现的具有活性的天然黄酮衍生物，可调节多种生物活性。

5-Hydroxy-7-acetoxyflavone Chemical Structure

CAS No. : 6674-40-4

规格	价格	是否有货
5 mg	￥2350	询问价格 & 货期
10 mg	￥4000	询问价格 & 货期

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生物活性	5-Hydroxy-7-acetoxyflavone, an active natural flavone derivative found in various plant sources, modulates several biological activities^[1].
分子量	296.27
Formula	C₁₇H₁₂O₅
CAS 号	6674-40-4
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Apilak Worachartcheewan, et al. Probing the origins of anticancer activity of chrysin derivatives. Medicinal Chemistry Research. May 2015, 24(5):1884-1892.

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7-Hydroxy-4-methyl-8-nitrocoumarin

发表于2025年9月19日由上海金畔生物科技有限公司

7-Hydroxy-4-methyl-8-nitrocoumarin

7-Hydroxy-4-methyl-8-nitrocoumarin 是一种香豆素衍生物。

7-Hydroxy-4-methyl-8-nitrocoumarin Chemical Structure

CAS No. : 19037-69-5

规格		是否有货
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25 mg		询价

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生物活性	7-Hydroxy-4-methyl-8-nitrocoumarin is a coumarin derivative^[1].
分子量	221.17
Formula	C₁₀H₇NO₅
CAS 号	19037-69-5
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Fadia Al-Haj Hussien, et al. Synthesis and Nitration of 7-Hydroxy-4-Methyl Coumarin via Pechmann Condensation Using Eco-Friendly Medias. International Letters of Chemistry, Physics and Astronomy. 2016, Vol. 69, pp 66-73.

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cis-4-Hydroxy-L-proline(Synonyms: 顺式-4-羟基-L-脯氨酸)

发表于2025年9月14日由上海金畔生物科技有限公司

cis-4-Hydroxy-L-proline (Synonyms: 顺式-4-羟基-L-脯氨酸) 纯度: ≥98.0%

cis-4-Hydroxy-L-proline，一种脯氨酸类似物，是胶原蛋白产生的抑制剂。cis-4-Hydroxy-L-proline 可通过阻止三层螺旋胶原在细胞层上的沉积从而抑制成纤维细胞的生长。cis-4-Hydroxy-L-proline 还可抑制原发性N-亚硝基甲基脲诱导的大鼠乳腺肿瘤的生长。

cis-4-Hydroxy-L-proline Chemical Structure

CAS No. : 618-27-9

规格	价格	是否有货
Free Sample (0.1-0.5 mg)		Apply now
10 mM * 1 mL in Water	￥550	In-stock
50 mg	￥500	In-stock
100 mg		询价
200 mg		询价

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cis-4-Hydroxy-L-proline 相关产品

•相关化合物库:

Natural Product Library Plus
Bioactive Compound Library Plus
Metabolism/Protease Compound Library
Natural Product Library
Anti-Cancer Compound Library
Peptidomimetic Library
Traditional Chinese Medicine Monomer Library
Food-Sourced Compound Library

生物活性

cis-4-Hydroxy-L-proline, a proline analogue, is an inhibitor of collagen production. cis-4-Hydroxy-L-proline could inhibit fibroblast growth by preventing the deposition of triple-helical collagen on the cell layer. cis-4-Hydroxy-L-proline also depresses the growth of primary N-nitrosomethylurea-induced rat mammary tumors^[1]^[2]^[3]^[4].

分子量

131.13

Formula

C₅H₉NO₃

CAS 号

618-27-9

中文名称

顺式-4-羟基-L-脯氨酸

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶解性数据

In Vitro:

H₂O : 100 mg/mL (762.60 mM; Need ultrasonic)

DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble or slightly soluble)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	7.6260 mL	38.1301 mL	76.2602 mL
5 mM	1.5252 mL	7.6260 mL	15.2520 mL
10 mM	0.7626 mL	3.8130 mL	7.6260 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

参考文献

[1]. Lewko WM, et, al. Sensitivity of N-nitrosomethylurea-induced rat mammary tumors to cis-hydroxyproline, an inhibitor of collagen production. Cancer Res. 1981 Jul;41(7):2855-62.

[2]. Kao WW, et, al. Proline analogue removes fibroblasts from cultured mixed cell populations. Nature. 1977 Mar 3;266(5597):63-4.

[3]. Tan EM, et, al. Proline analogues inhibit human skin fibroblast growth and collagen production in culture. J Invest Dermatol. 1983 Apr;80(4):261-7.

[4]. Riley DJ, et, al. Prevention of bleomycin-induced pulmonary fibrosis in the hamster by cis-4-hydroxy-l-proline. Am Rev Respir Dis. 1981 Apr;123(4 Pt 1):388-93.

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2-Hydroxy Ibuprofen(Synonyms: 2-羟基布洛芬; (±)-2-Hydroxy Ibuprofen)

发表于2025年9月11日由上海金畔生物科技有限公司

2-Hydroxy Ibuprofen (Synonyms: 2-羟基布洛芬; (±)-2-Hydroxy Ibuprofen)

2-Hydroxy Ibuprofen 是 Ibuprofen 的一种代谢产物。Ibuprofen 是 COX-1 和 COX-2 的抑制剂，IC₅₀ 值分别为 13 μM 和 370 μM，具有抗炎的活性。

2-Hydroxy Ibuprofen Chemical Structure

CAS No. : 51146-55-5

规格	价格	是否有货
5 mg	￥2000	询问价格 & 货期

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生物活性	2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC₅₀s of 13 μM and 370 μM, respectively.
分子量	222.28
Formula	C₁₃H₁₈O₃
CAS 号	51146-55-5
中文名称	2-羟基布洛芬
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7.

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Hydroxy-PEG4-acid

发表于2025年9月8日由上海金畔生物科技有限公司

Hydroxy-PEG4-acid

Hydroxy-PEG4-acid 是一种不可降解 (non-cleavable) 的含 4 个单元 PEG 的ADC linker，可用于合成抗体偶联药物 (ADC)。Hydroxy-PEG4-acid 还是一种 PROTAC linker，属于 PEG 类，可用于合成 PROTAC 分子。

Hydroxy-PEG4-acid Chemical Structure

CAS No. : 937188-59-5

规格		是否有货
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生物活性

Hydroxy-PEG4-acid is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target^[1]

Non-cleavable

PEGs

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker^[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

266.29

Formula

C₁₁H₂₂O₇

CAS 号

937188-59-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

参考文献

[1]. Tinya Abrams, et al. Antibody drug conjugates. WO2016203432A1.

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Hydroxy-PEG2-C2-sulfonic acid

发表于2025年9月6日由上海金畔生物科技有限公司

Hydroxy-PEG2-C2-sulfonic acid

Hydroxy-PEG2-C2-sulfonic acid 是一种 PROTAC linker，属于 PEG 类。Hydroxy-PEG2-C2-sulfonic acid 可用于合成一系列 PROTAC 分子。

Hydroxy-PEG2-C2-sulfonic acid Chemical Structure

CAS No. : 112724-27-3

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250 mg		询价
500 mg		询价

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生物活性

Hydroxy-PEG2-C2-sulfonic acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

IC₅₀ & Target^[1]

PEGs

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

214.24

Formula

C₆H₁₄O₆S

CAS 号

112724-27-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Upali Weersooriya, et al. Process for preparing isethionate ethoxylates. WO9529144A1

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Hydroxy-PEG10-Boc

发表于2025年9月4日由上海金畔生物科技有限公司

Hydroxy-PEG10-Boc

Hydroxy-PEG10-Boc 来源于专利文献 CN108707228 (例 0024)。Hydroxy-PEG10-Boc 是一种用于合成抗体偶联药物 (ADC) 的不可降解 (non-cleavable) 的 ADC linker。Hydroxy-PEG10-Boc 可与紫杉醇 (HY-B0015) 或多西他赛 (HY-B0011) 结合。

Hydroxy-PEG10-Boc Chemical Structure

CAS No. : 778596-26-2

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生物活性

Hydroxy-PEG10-Boc is extacted from patent CN108707228 (example 0024)^[1]. Hydroxy-PEG10-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG10-Boc can be conjugated to Paclitaxel (HY-B0015) or docetaxel (HY-B0011)^[2].

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

586.71

Formula

C₂₇H₅₄O₁₃

CAS 号

778596-26-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

参考文献

[1]. Huli, et al. A kind of preparation method of hydroxyl polyethylene glycol propionic ester. Patent CN108707228A.

[2]. Miller ML, et al. Synthesis of taxoids with improved cytotoxicity and solubility for use in tumor-specific delivery.J Med Chem. 2004 Sep 23;47(20):4802-5.

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N-Boc-cis-4-hydroxy-L-proline

发表于2025年8月10日由上海金畔生物科技有限公司

N-Boc-cis-4-hydroxy-L-proline

N-Boc-cis-4-hydroxy-L-proline 是不可降解 (non-cleavable) 的 ADC linker，用于合成抗体偶联药物 (ADCs)。N-Boc-cis-4-hydroxy-L-proline 也是一个基于烷基链 (alkyl chain) 的 PROTAC linker，可用于合成 PROTAC。

N-Boc-cis-4-hydroxy-L-proline Chemical Structure

CAS No. : 87691-27-8

规格	价格	是否有货
500 mg	￥350	In-stock
1 g		询价
5 g		询价

* Please select Quantity before adding items.

生物活性

N-Boc-cis-4-hydroxy-L-proline is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-cis-4-hydroxy-L-proline is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs^[1]^[2

IC₅₀ & Target

Non-cleavable

体外研究
(In Vitro)

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

231.25

Formula

C₁₀H₁₇NO₅

CAS 号

87691-27-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

参考文献

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.

[2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

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Hydroxy-PEG2-C2-PFP ester

发表于2025年8月10日由上海金畔生物科技有限公司

Hydroxy-PEG2-C2-PFP ester

Hydroxy-PEG2-C2-PFP ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.

Hydroxy-PEG2-C2-PFP ester Chemical Structure

CAS No. : 1820673-42-4

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

Hydroxy-PEG2-C2-PFP ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.

IC₅₀ & Target

PEGs	Alkyl/ether

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

344.23

Formula

C₁₃H₁₃F₅O₅

CAS 号

1820673-42-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

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Hydroxy-PEG2-CH2-Boc

发表于2025年8月10日由上海金畔生物科技有限公司

Hydroxy-PEG2-CH2-Boc

Hydroxy-PEG2-C2-PFP ester 是一种基于 PEG 和 Alkyl/ether 结构的 PROTAC linker。Hydroxy-PEG2-C2-PFP ester 可用于合成一系列 PROTAC 分子。

Hydroxy-PEG2-CH2-Boc Chemical Structure

CAS No. : 149299-82-1

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

Hydroxy-PEG2-CH2-Boc is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

220.26

Formula

C₁₀H₂₀O₅

CAS 号

149299-82-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

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Hydroxy-PEG3-SS-PEG3-alcohol

发表于2025年6月10日由上海金畔生物科技有限公司

Hydroxy-PEG3-SS-PEG3-alcohol

Hydroxy-PEG3-SS-PEG3-alcohol 是一种可降解 (cleavable) 的含 6 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

Hydroxy-PEG3-SS-PEG3-alcohol Chemical Structure

CAS No. : 5662-81-7

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

Hydroxy-PEG3-SS-PEG3-alcohol is also a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)^[1].

IC₅₀ & Target

Cleavable

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker^[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

418.57

Formula

C₁₆H₃₄O₈S₂

CAS 号

5662-81-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Barrientos AG, et al. Gold glyconanoparticles: synthetic polyvalent ligands mimicking glycocalyx-like surfaces as tools for glycobiological studies. Chemistry. 2003 May 9;9(9):1909-21.

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6-Bromo-2-hydroxy-3-methoxybenzaldehyde(Synonyms: NSC95682)

发表于2025年5月3日由上海金畔生物科技有限公司

6-Bromo-2-hydroxy-3-methoxybenzaldehyde (Synonyms: NSC95682) 纯度: 99.55%

6-Bromo-2-hydroxy-3-methoxybenzaldehyde (NSC95682) 是一个 IRE-1α 抑制剂，其 IC₅₀ 值为 0.08 μM，来自专利 WO 2008154484 A1, 实例 IRE-lα 抑制剂化合物 3-5。

6-Bromo-2-hydroxy-3-methoxybenzaldehyde Chemical Structure

CAS No. : 20035-41-0

规格	价格	是否有货
10 mM * 1 mL in DMSO	￥660	In-stock
50 mg	￥600	In-stock
100 mg		询价
200 mg		询价

* Please select Quantity before adding items.

6-Bromo-2-hydroxy-3-methoxybenzaldehyde 相关产品

•相关化合物库:

Covalent Screening Library Plus
Bioactive Compound Library Plus
Cell Cycle/DNA Damage Compound Library
Kinase Inhibitor Library
Anti-Cancer Compound Library
Anti-Aging Compound Library
Covalent Screening Library
Endoplasmic Reticulum Stress Compound Library
Targeted Diversity Library

生物活性

6-Bromo-2-hydroxy-3-methoxybenzaldehyde (NSC95682) is an IRE-1α inhibitor with an IC₅₀ of 0.08 μM, extracted from patent WO 2008154484 A1, IRE-lα inhibitor compound 3-5.

IC₅₀ & Target

IC50: 0.08 μM (IRE-1α)^[1]

分子量

231.04

Formula

C₈H₇BrO₃

CAS 号

20035-41-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶解性数据

In Vitro:

DMSO : 113 mg/mL (489.09 mM; Need ultrasonic and warming)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	4.3283 mL	21.6413 mL	43.2826 mL
5 mM	0.8657 mL	4.3283 mL	8.6565 mL
10 mM	0.4328 mL	2.1641 mL	4.3283 mL

参考文献

[1]. John Bruce Patterson, et al. Ire-1a inhibitors. WO 2008154484 A1

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Hydroxy-PEG12-Boc

发表于2025年5月3日由上海金畔生物科技有限公司

Hydroxy-PEG12-Boc

Hydroxy-PEG12-Boc 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

Hydroxy-PEG12-Boc Chemical Structure

CAS No. : 2388521-20-6

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

Hydroxy-PEG12-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

PEGs	Alkyl/ether

体外研究
(In Vitro)

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

674.81

Formula

C₃₁H₆₂O₁₅

CAS 号

2388521-20-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

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Hydroxy-PEG13-Boc

发表于2025年5月3日由上海金畔生物科技有限公司

Hydroxy-PEG13-Boc

Hydroxy-PEG13-Boc 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

Hydroxy-PEG13-Boc Chemical Structure

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

Hydroxy-PEG13-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

PEGs	Alkyl/ether

体外研究
(In Vitro)

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

718.87

Formula

C₃₃H₆₆O₁₆

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

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whatman (沃特曼)

英国沃特曼 Millipore PALL中国代理商金畔官网

标签归档：hydroxy

Cas(113775-22-7), (1S,4S)-3-氧代-2-氧杂-5-氮杂双环[2.2.1]庚烷-5-羧酸叔丁酯, N-Boc-4-hydroxy-L-pyrrolidine lactone,Boc-4-hydroxy-L-pyrrolidine lactone,

(1S,4S)-3-氧代-2-氧杂-5-氮杂双环[2.2.1]庚烷-5-羧酸叔丁酯

基本信息

安全信息

相关属性

Cas(113775-22-7), (1S,4S)-3-氧代-2-氧杂-5-氮杂双环[2.2.1]庚烷-5-羧酸叔丁酯, N-Boc-4-hydroxy-L-pyrrolidine lactone,Boc-4-hydroxy-L-pyrrolidine lactone,

(1S,4S)-3-氧代-2-氧杂-5-氮杂双环[2.2.1]庚烷-5-羧酸叔丁酯

基本信息

相关属性

TLR7/8 agonist 4 hydroxy-PEG10-acid

S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate

TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride

Hydroxy-PEG3-(CH2)2-Boc

5-Hydroxy-7-acetoxyflavone

7-Hydroxy-4-methyl-8-nitrocoumarin

cis-4-Hydroxy-L-proline(Synonyms: 顺式-4-羟基-L-脯氨酸)

cis-4-Hydroxy-L-proline 相关产品

•相关化合物库:

2-Hydroxy Ibuprofen(Synonyms: 2-羟基布洛芬; (±)-2-Hydroxy Ibuprofen)

Hydroxy-PEG4-acid

Hydroxy-PEG2-C2-sulfonic acid

Hydroxy-PEG10-Boc

N-Boc-cis-4-hydroxy-L-proline

Hydroxy-PEG2-C2-PFP ester

Hydroxy-PEG2-CH2-Boc

Hydroxy-PEG3-SS-PEG3-alcohol

6-Bromo-2-hydroxy-3-methoxybenzaldehyde(Synonyms: NSC95682)

6-Bromo-2-hydroxy-3-methoxybenzaldehyde 相关产品

•相关化合物库:

Hydroxy-PEG12-Boc

Hydroxy-PEG13-Boc