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Goserelin acetate (Synonyms: 醋酸戈舍瑞林; ICI-118630 acetate) 纯度: 99.23%
Goserelin acetate (ICI-118630 acetate) 是一种促性腺激素释放激素 (GnRH/LHRH) 十肽类似物,能作为 GnRH 激动剂。Goserelin acetate 可用于乳腺癌、上皮性卵巢癌和前列腺癌的研究。
Goserelin acetate Chemical Structure
CAS No. : 145781-92-6
规格 | 价格 | 是否有货 | 数量 |
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10 mM * 1 mL in DMSO | ¥1930 | In-stock | |
5 mg | ¥910 | In-stock | |
10 mg | ¥1320 | In-stock | |
50 mg | ¥4620 | In-stock | |
100 mg | 询价 | ||
200 mg | 询价 |
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Goserelin acetate 相关产品
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生物活性 |
Goserelin acetate (ICI-118630 acetate), a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH), functions as a GnRH agonist. Goserelin acetate can be used for the research of breast cancer, epithelial ovarian cancer and prostate cancer[1][2]. |
IC50 & Target |
GnRH[1] |
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体外研究 (In Vitro) |
Goserelin (1 nM-1 mM; 48-72 hours) promotes EOC cell apoptosis[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. Apoptosis Analysis[1]
Western Blot Analysis[1]
RT-PCR[1]
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体内研究 (In Vivo) |
Goserelin (100 µg; s.c.; daily; for 19 days) significantly increases the proportion of apoptotic cells in the subcutaneous xenograft tumors[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
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Clinical Trial |
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分子量 |
1329.46 |
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Formula |
C61H88N18O16 |
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CAS 号 |
145781-92-6 |
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中文名称 |
醋酸戈舍瑞林 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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溶解性数据 |
In Vitro:
H2O : 100 mg/mL (75.22 mM; Need ultrasonic) DMSO : ≥ 28 mg/mL (21.06 mM) * “≥” means soluble, but saturation unknown. 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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