VH032-thiol-C6-NH2(Synonyms: VHL Ligand-Linker Conjugates 14; E3 ligase Ligand-Linker Conjugates 29)

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VH032-thiol-C6-NH2 (Synonyms: VHL Ligand-Linker Conjugates 14; E3 ligase Ligand-Linker Conjugates 29)

VH032-thiol-C6-NH2 (VHL Ligand-Linker Conjugates 14) 是一种合成的 E3 连接酶配体-linker 偶联物,包含基于 VH032 的 VHL 配体和 1 个 linker。

VH032-thiol-C6-NH2(Synonyms: VHL Ligand-Linker Conjugates 14;  E3 ligase Ligand-Linker Conjugates 29)

VH032-thiol-C6-NH2 Chemical Structure

CAS No. : 2098836-63-4

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生物活性

VH032-thiol-C6-NH2 (VHL Ligand-Linker Conjugates 14) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology.

IC50 & Target

VHL

 

体外研究
(In Vitro)

VH032-thiol-C6-NH2 (VHL Ligand-Linker Conjugates 14) is a compound binding to BRD4, used to inhibit BRD4 based on PROTAC[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

589.81

Formula

C29H43N5O4S2

CAS 号

2098836-63-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.

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