BCR-ABL-IN-1

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

BCR-ABL-IN-1 

BCR-ABL-IN-1 是一种 BCR-ABL 酪氨酸激酶抑制剂，pIC50 值为 6.46，可能用于慢性髓细胞白血病的研究。

BCR-ABL-IN-1

BCR-ABL-IN-1 Chemical Structure

CAS No. : 188260-50-6

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生物活性

BCR-ABL-IN-1 is an inhibitor of BCR-ABL tyrosine kinase, with a pIC50 of 6.46, and may be used in the research of chronic myelogenous leukemia.

IC50 & Target

pIC50: 6.46 (BCR-ABL)[1]
体外研究
(In Vitro)

BCR-ABL-IN-1 (Compound 21) is an inhibitor of BCR-ABL tyrosine kinase, with a pIC50 of 6.46, and may be used in the research of chronic myelogenous leukemia.

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

459.44

Formula

C23H21F4N5O
CAS 号

188260-50-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Cui J1, et al. BCR-ABL tyrosine kinase inhibitor pharmacophore model derived from a series of phenylaminopyrimidine-based (PAP) derivatives. Bioorg Med Chem Lett. 2013 Apr 15;23(8):2442-50.

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