KRAS G12C inhibitor 5

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KRAS G12C inhibitor 5 

KRAS G12C inhibitor 5 是一种 KRas G12C 抑制剂,详细信息请参考专利文献 WO2017201161A1 中的化合物 147。

KRAS G12C inhibitor 5

KRAS G12C inhibitor 5 Chemical Structure

CAS No. : 2158297-63-1

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生物活性

KRAS G12C inhibitor 5 is a KRas G12C inhibitor extracted from patent WO2017201161A1, Compound example 147[1].

IC50 & Target[1]

KRas G12C

 

体外研究
(In Vitro)

Kirsten Rat Sarcoma 2 Viral Oncogene Homolog (KRas) is a small GTPase and a member of the Ras family of oncogenes. KRas serves a molecular switch cycling between inactive (GDP -bound) and active (GTP -bound) states to transduce upstream cellular signals received from multiple tyrosine kinases to downstream effectors to regulate a wide variety of processes, including cellular proliferation[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

551.68

Formula

C32H37N7O2

CAS 号

2158297-63-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. John P. Fischer, et al. Kras g12c inhibitors. WO2017201161A1.

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