Alflutinib(Synonyms: Furmonertinib; AST2818)

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Alflutinib (Synonyms: Furmonertinib; AST2818)

Alflutinib is a potent inhibitor of EGFR. Alflutinib inhibits EGFR active mutations as well as the T790M acquired resistant mutation. Alflutinib has the potential for the research of cancer diseases, especially non-small cell lung cancer (NSCLC).

Alflutinib(Synonyms: Furmonertinib; AST2818)

Alflutinib Chemical Structure

CAS No. : 1869057-83-9

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Alflutinib 的其他形式现货产品:

Alflutinib mesylate

生物活性

Alflutinib is a potent inhibitor of EGFR. Alflutinib inhibits EGFR active mutations as well as the T790M acquired resistant mutation. Alflutinib has the potential for the research of cancer diseases, especially non-small cell lung cancer (NSCLC)[1].

IC50 & Target[1]

EGFR

 

体外研究
(In Vitro)

AST2818 is designed to inhibit EGFR active mutations as well as the T790M acquired resistant mutation[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

568.59

Formula

C28H31F3N8O2
CAS 号

1869057-83-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Y. Shi, et al. P2.03-028 Third Generation EGFR Inhibitor AST2818 (Alflutinib) in NSCLC Patients with EGFR T790M Mutation: A phase1/2 Multi-Center Clinical Trial.

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