上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
OXA-01
OXA-01 是有效的 mTORC1 和 mTORC2 抑制剂,其 IC50 值分别为 29 nM 和 7 nM。

OXA-01 Chemical Structure
CAS No. : 936889-68-8
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100 mg | 询价 | ||
250 mg | 询价 | ||
500 mg | 询价 |
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生物活性 |
OXA-01 is a potent mTORC1 and mTORC2 inhibitor, with IC50 values of 29 nM and 7 nM, respectively[1]. |
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体内研究 (In Vivo) |
OXA-01 demonstrated broad anti-tumor activity in several different human xenograft models of various histologies. Furthermore, in GEO and Colo-205 colon xenograft models, OXA-01 demonstrated 100% TGI, whilst rapamycin treatment resulted in only 75% and 53% TGI, respectively[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
分子量 |
409.87 |
Formula |
C21H20ClN5O2 |
CAS 号 |
936889-68-8 |
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
参考文献 |
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