上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。
Antitumor agent-45
Antitumor agent-45 (Compound 21) 可诱导 A549 细胞凋亡并将细胞阻滞在 G0/G1 和 G2/M期。Antitumor agent-45 (Compound 21) 抑制c-Met 表达。
Antitumor agent-45 Chemical Structure
CAS No. : 2581082-74-6
| 规格 | 是否有货 | ||
|---|---|---|---|
| 100 mg | 询价 | ||
| 250 mg | 询价 | ||
| 500 mg | 询价 |
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| 生物活性 |
Antitumor agent-45 (Compound 21) could induce and stimulate A549 cells apoptosis in G0/G1 and G2/M phase. Antitumor agent-45 (Compound 21) inhibits c-Met expression to regulate the growth of tumor cells[1]. |
|---|---|
| 体外研究 (In Vitro) |
Antitumor agent-45 (Compound 21) enhibits IC50 values of 1.06, 10.87 and 0.11 μM in A549, Hela and MCF-7 cells, respectively[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
| 分子量 |
570.37 |
| Formula |
C28H17BrFN5O3 |
| CAS 号 |
2581082-74-6 |
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| 参考文献 |
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