N,N-Dimethylsphingosine

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N,N-Dimethylsphingosine 

N,N-Dimethylsphingosine 是 SphK (鞘氨醇激酶)的有效抑制剂，在多种组织和肿瘤细胞系中是鞘氨醇的内源性代谢产物。

N,N-Dimethylsphingosine

N,N-Dimethylsphingosine Chemical Structure

CAS No. : 119567-63-4

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生物活性

N,N-Dimethylsphingosine is a potent inhbitor of SphK (sphingosine kinase) as an endogenous metabolite of sphingosine produced in various tissues and tumor cell lines[1].

分子量

327.55

Formula

C20H41NO2
CAS 号

119567-63-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Endo K, et al. Cell membrane signaling as target in cancer therapy: inhibitory effect of N,N-dimethyl and N,N,N-trimethyl sphingosine derivatives on in vitro and in vivo growth of human tumor cells in nude mice. Cancer Res.

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