CC214-2

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

CC214-2 

CC214-2 是一种有效的 mTORC1/mTORC2 双重抑制剂。结核分枝杆菌调节哺乳动物雷帕霉素靶蛋白 (mTOR) 信号传导以阻止自噬。CC214-2 有可能缩短结核病的持续时间。

CC214-2

CC214-2 Chemical Structure

CAS No. : 1228012-18-7

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生物活性

CC214-2 is a potent and dual inhibitor of mTORC1/mTORC2. Mycobacterium tuberculosis modulates mammalian target of rapamycin (mTOR) signaling to impede autophagy. CC214-2 has the potential to shorten the duration of TB[1].

分子量

383.44

Formula

C20H25N5O3
CAS 号

1228012-18-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Tasneen R, et al. Dual mTORC1/mTORC2 Inhibition as a Host-Directed Therapeutic Target in Pathologically Distinct Mouse Models of Tuberculosis. Antimicrob Agents Chemother. 2021;65(7):e0025321.

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