TASIN-1

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

TASIN-1 

TASIN-1 是截短的 APC 基因(结肠腺瘤样息肉基因)选择性抑制剂,通过抑制胆固醇生物合成发挥细胞毒性作用。TASIN-1 代表了一种潜在的治疗策略,用于预防和干预 APC 突变型结直肠癌。

TASIN-1

TASIN-1 Chemical Structure

CAS No. : 792927-06-1

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生物活性

TASIN-1 is a selective inhibitor of truncated APC gene (adenomatous polyposis coli gene) and exerts cytotoxic effects through inhibition of cholesterol biosynthesis. TASIN-1 represents a potential therapeutic strategy for prevention and intervention in CRC with mutant APC[1].

分子量

352.49

Formula

C18H28N2O3S

CAS 号

792927-06-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Zhang L, et al. Selective targeting of mutant adenomatous polyposis coli (APC) in colorectal cancer. Sci Transl Med. 2016 Oct 19;8(361):361ra140.

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