Antitumor agent-48

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Antitumor agent-48 

Antitumor agent-48 (Compound 4a) 是一种具有抗肿瘤活性的 2,3-dehydrosilybin 衍生物。Antitumor agent-48 对 MCF-7、NCI-H1299、HepG2 和 HT29 细胞具有细胞毒活性，IC50 值分别为 8.06 µM、13.1 µM、16.51 µM 和 12.44 µM。

Antitumor agent-48

Antitumor agent-48 Chemical Structure

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生物活性

Antitumor agent-48 (Compound 4a) is a 2,3-dehydrosilybin derivative with an antitumor activity. Antitumor agent-48 shows cytotoxic activity against MCF-7, NCI-H1299, HepG2 and HT29 cells with IC50 values of 8.06 µM, 13.1 µM, 16.51 µM and 12.44 µM, respectively[1].

分子量

706.65

Formula

C35H34N2O14
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Qiuchan Wu, et al. Synthesis and antitumor activity of novel silibinin and 2,3-dehydrosilybin derivatives with carbamate groups. Med Chem Res. 2022;31(4):533-544.

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