PI3Ka-IN-5

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

PI3Ka-IN-5 

PI3Ka-IN-5 (compound 6 ab) 是一种有效的 PI3Kα/mTOR 抑制剂，IC50 值分别为 0.7 nM 和 3.3 nM。PI3Ka-IN-5 可用于结直肠癌的研究。

PI3Ka-IN-5

PI3Ka-IN-5 Chemical Structure

CAS No. : 2237953-19-2

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生物活性

PI3Ka-IN-5 (compound 6 ab) is a potent PI3Kα/mTOR inhibitor, with an IC50 of 0.7 nM and 3.3 nM, respectively. PI3Ka-IN-5 can be used for the research of colorectal cancer[1].

IC50 & Target[1]

PI3Kα

0.7 nM (IC50)

mTOR

3.3 nM (IC50)

分子量

601.66

Formula

C30H35N9O5
CAS 号

2237953-19-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Wu CF, et, al. Synthesis and bioevaluation of diaryl urea derivatives as potential antitumor agents for the treatment of human colorectal cancer. Eur J Med Chem. 2022 Feb 5;229:114055.

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