Panepoxydone

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Panepoxydone 

Panepoxydone 是一种 NF-κB 活化抑制剂。Panepoxydone 通过抑制 IκB 的磷酸化来干扰 NF-κB 介导的信号转导。Panepoxydone 具有抗肿瘤、抗炎、抗疟疾和抗寄生虫活性。

Panepoxydone

Panepoxydone Chemical Structure

CAS No. : 31298-54-1

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生物活性

Panepoxydone is an inhibitor of NF-κB activation. Panepoxydone interferes with the NF-κB mediated signal transduction by inhibiting the phosphorylation of IκB. Panepoxydone exhibits antitumor, anti-inflammatory, antimalarial and anti-parasitic activity[1][2].

分子量

210.23

Formula

C11H14O4
CAS 号

31298-54-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Arora R, et, al. Panepoxydone targets NF-kB and FOXM1 to inhibit proliferation, induce apoptosis and reverse epithelial to mesenchymal transition in breast cancer. PLoS One. 2014 Jun 4;9(6):e98370.

    [2]. Erkel G, et, al. Influence of the fungal NF-kappaB inhibitor panepoxydone on inflammatory gene expression in MonoMac6 cells. Int Immunopharmacol. 2007 May;7(5):612-24.

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