ER 50891 | whatman (沃特曼)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

ER 50891

ER-50891 是一种有效的视黄酸受体 α (RARα) 拮抗剂。ER-50891 显着减弱 ATRA 对 BMP 2 诱导的成骨细胞生成的抑制作用。

ER 50891 Chemical Structure

CAS No. : 187400-85-7

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生物活性	ER-50891 is a potent antagonist of retinoic acid receptor α(RARα). ER-50891 significantly attenuates ATRA’s inhibitive effects on BMP 2-induced osteoblastogenesis^[1].
IC₅₀ & Target	RARα^[1]
分子量	432.51
Formula	C₂₉H₂₄N₂O₂
CAS 号	187400-85-7
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Batran RZ, et al. New quinolone derivatives as neuropeptide S receptor antagonists: Design, synthesis, homology modeling, dynamic simulations and modulation of Gq/Gs signaling pathways. Bioorg Chem. 2021;111:104817.

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