NSC 828467

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

NSC 828467 

NSC 828467具有显著的体外抗癌活性，是前五大CA-IX抑制剂之一，其IC50值为27.2nM。

NSC 828467

NSC 828467 Chemical Structure

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生物活性

NSC 828467 exhibited significant in vitro anticancer activity,and it is one of the top-five CA IX inhibitors with an IC50 value of 27.2nM.

IC50 & Target

HCA IX

27.2 nM (IC50)

分子量

461.50

Formula

C21H19N9O2S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Tawfik HO, et al. Discovery of new carbonic anhydrase IX inhibitors as anticancer agents by toning the hydrophobic and hydrophilic rims of the active site to encounter the dual-tail approach. Eur J Med Chem. 2022 Feb 12;232:114190.

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