ML-099(Synonyms: CID-888706)

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ML-099 (Synonyms: CID-888706)

ML-099 (CID-888706) 是一种泛 Ras 相关 GTPases 激活剂,可以激活 Rac1cell division cycle 42RasRab7Rab-2A

ML-099(Synonyms: CID-888706)

ML-099 Chemical Structure

CAS No. : 496775-95-2

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生物活性

ML-099 (CID-888706) is a pan Ras-related GTPases activator that can activate Rac1, cell division cycle 42, Ras, Rab7, and Rab-2A[1].

体外研究
(In Vitro)

ML-099 activates cell division cycle 42 activated mutant, cell division cycle 42 wild type, Ras protein wild type, GTP-binding protein (Rab7), Rab-2A, Rac1 protein activated mutant, Rac1 protein wild type, and Ras protein activated mutant with EC50 values of 58.88 nM, 100 nM, 141.25 nM, 181.97 nM, 354.81 nM, 25.42 nM, 20.17 nM and 95.5 nM, respectively[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

259.32

Formula

C14H13NO2S

CAS 号

496775-95-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Surviladze, Z., et al. UNMCMD Probe Report: Three small molecule pan activator families of Ras-related GTPases. 1-42 (2010-2009 May 18).

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