CDK/HDAC-IN-1

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

CDK/HDAC-IN-1 

CDK/HDAC-IN-1 显示出显著的 CDK2/4/6 和 HDAC6 抑制活性（IC50 = 60.9 ± 2.9, 276 ± 22.3, 27.2 ± 4.2, 和 128.6 ± 0.4 nM）。

CDK/HDAC-IN-1

CDK/HDAC-IN-1 Chemical Structure

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生物活性

CDK/HDAC-IN-1 shows remarkable CDK2/4/6 and HDAC6 inhibitory activity of IC50 = 60.9 ± 2.9, 276 ± 22.3, 27.2 ± 4.2, and 128.6 ± 0.4 nM, respectively.

分子量

378.38

Formula

C20H18N4O4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Cao Z, et al. Indirubin Derivatives as Dual Inhibitors Targeting Cyclin-Dependent Kinase and Histone Deacetylase for Treating Cancer. J Med Chem. 2021 Oct 28;64(20):15280-15296.

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