Eribulin-d3 mesylate(Synonyms: 甲磺酸艾日布林 d3 (甲磺酸盐))

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Eribulin-d3 mesylate (Synonyms: 甲磺酸艾日布林 d3 (甲磺酸盐))

Eribulin-d3 mesylate 是 Eribulin mesylate 的氘代物。Eribulin mesylate 是靶向微管 (microtubule) 的抗癌剂，可用于研究癌症。

Eribulin-d3 mesylate(Synonyms: 甲磺酸艾日布林 d3 (甲磺酸盐))

Eribulin-d3 mesylate Chemical Structure

规格 价格 是否有货
1 mg ￥108000 询问价格 & 货期

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生物活性

Eribulin-d3 mesylate is a deuterium labeled Eribulin mesylate. Eribulin mesylate is a microtubule targeting agent that is used for the research of cancer[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

829.02

Formula

C41H60D3NO14S
中文名称

甲磺酸艾日布林 d3 (甲磺酸盐)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et, al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

    [2]. Watanabe K, et, al. Low-dose eribulin reduces lung metastasis of osteosarcoma in vitro and in vivo. Oncotarget. 2019 Jan 4;10(2):161-174.

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