Berberine-d6 chloride(Synonyms: Natural Yellow 18-d6 chloride)

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Berberine-d6 chloride (Synonyms: Natural Yellow 18-d6 chloride)

Berberine-d6 (Natural Yellow 18-d6) chloride 是 Berberine chloride 的氘代物。Berberine chloride 是一种生物碱,常用作抗生素。Berberine chloride 诱导活性氧 (ROS) 生成并抑制 DNA 拓扑异构酶 (topoisomerase)。抗肿瘤特性。

Berberine-d6 chloride(Synonyms: Natural Yellow 18-d6 chloride)

Berberine-d6 chloride Chemical Structure

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生物活性

Berberine-d6 (Natural Yellow 18-d6) chloride is the deuterium labeled Berberine chloride. Berberine chloride is an alkaloid that acts as an antibiotic. Berberine chloride induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

377.85

Formula

C20H12D6ClNO4

中文名称

盐酸小檗碱 d6 (氯化物)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Cai Y, et al. Berberine inhibits the growth of human colorectal adenocarcinoma in vitro and in vivo. J Nat Med. 2014 Jan;68(1):53-62.

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