STK33-IN-1

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

STK33-IN-1 

STK33-IN-1 (compound 1) 是STK33 的抑制剂,其 IC50 值为 7 nM。

STK33-IN-1

STK33-IN-1 Chemical Structure

CAS No. : 1404437-49-5

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生物活性

STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC50 of 7 nM[1].

IC50 & Target

IC50: 7 nM (STK33)[1].

体外研究
(In Vitro)

STK33-IN-1 (compound 1) is 2-fold selective for Aurora-B (AurB) versus STK33. STK33-IN-1 (compound 1) has proven unsuccessful in selectively killing KRAS-dependent cancer cell lines[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

445.52

Formula

C24H27N7O2

CAS 号

1404437-49-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Michel Weïwer, et al. A Potent and Selective Quinoxalinone-Based STK33 Inhibitor Does Not Show Synthetic Lethality in KRAS-Dependent Cells. ACS Med Chem Lett. 2012 Dec 13;3(12):1034-1038.

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