UCM 608(Synonyms: 2-Phenylmelatonin)

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

UCM 608 (Synonyms: 2-Phenylmelatonin)

UCM 608 是一种高亲和力的褪黑素 (MT) 膜受体激动剂。MT1 和MT2 的pKi 值分别为 10.7 和 10.4。

UCM 608(Synonyms: 2-Phenylmelatonin)

UCM 608 Chemical Structure

CAS No. : 151889-03-1

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生物活性

UCM 608 is a high affinity melatonin (MT) membrane receptor agonist. The pKi values for MT1 and MT2 are 10.7 and 10.4[1][2].

IC50 & Target

pKi: 10.7 (MT1)[1].
pKi: 10.4 (MT2)[1]
体外研究
(In Vitro)

UCM 608 is a high affinity melatonin membrane receptor agonist. The pKi values for MT1 and MT2 are 10.7 and 10.4 [1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

308.37

Formula

C19H20N2O2
CAS 号

151889-03-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Radogna F, et al. Rapid and transient stimulation of intracellular reactive oxygen species by melatonin in normal and tumor leukocytes. Toxicol Appl Pharmacol. 2009;239(1):37-45.

    [2]. Mor, M., et al. Synthesis, pharmacological characterization and QSAR studies on 2-substituted indole melatonin receptor ligands. Bioorganic & Medicinal Chemistry, 9(4), 1045–1057.

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