MDM2-IN-21

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

MDM2-IN-21 

MDM2-IN-21 是一种有效的 MDM2 抑制剂。MDM2-IN-21 可用于癌症研究。

MDM2-IN-21

MDM2-IN-21 Chemical Structure

CAS No. : 939981-88-1

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生物活性

MDM2-IN-21 is a potent MDM2 inhibitor. MDM2-IN-21 can be used for the research of cancer[1].

IC50 & Target

MDM2[1]

体外研究
(In Vitro)

The IC50 values of MDM2-IN-21 are 0.03 μM and 0.8 μM in homogeneous time resolved fluorescence (HTRF) assay and the wild-type p53 cell lines[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

607.61

Formula

C34H40Cl2N4O2

CAS 号

939981-88-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Vu B, et al. Discovery of RG7112: A Small-Molecule MDM2 Inhibitor in Clinical Development. ACS Med Chem Lett. 2013;4(5):466-469.

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