Thymectacin(Synonyms: NB1011)

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Thymectacin (Synonyms: NB1011)

Thymectacin (NB1011) 是一种选择性靶向高表达胸腺嘧啶合成酶 (TS) 的肿瘤细胞的化合物。Thymectacin 是 BVdU (brivudin) 的芳氧基磷酸化衍生物。

Thymectacin(Synonyms: NB1011)

Thymectacin Chemical Structure

CAS No. : 232925-18-7

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生物活性

Thymectacin (NB1011) is an agent selectively targeting tumor cells that have a high expression of thymidylate synthase (TS). Thymectacin is an aryloxy phosphoramidate derivative of BVdU (brivudin)[1][2].

体外研究
(In Vitro)

Thymectacin (NB1011) is an agent selectively targeting tumor cells that have a high expression of thymidylate synthase (TS)[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

分子量

574.32

Formula

C21H25BrN3O9P

CAS 号

232925-18-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Wilson RH. Novel therapeutic developments other than EGFR and VEGF inhibition in colorectal cancer. Oncologist. 2006;11(9):1018-1024.

    [2]. Congiatu C, et al. Novel potential anticancer naphthyl phosphoramidates of BVdU: separation of diastereoisomers and assignment of the absolute configuration of the phosphorus center. J Med Chem. 2006;49(2):452-455.

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