Pyrene azide 3

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Pyrene azide 3 

Pyrene azide 3 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Pyrene azide 3

Pyrene azide 3 Chemical Structure

CAS No. : 2252168-06-0

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生物活性

Pyrene azide 3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

444.53

Formula

C26H28N4O3

CAS 号

2252168-06-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1014.

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