AC-261066

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

AC-261066 

AC-261066 是一种高效、口服有效的、亚型选择性的 RARbeta2 受体激动剂，其 pEC50 为 8.0 。

AC-261066

AC-261066 Chemical Structure

CAS No. : 870773-76-5

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生物活性

AC-261066 is a potent, orally available and isoform-selective retinoic acid beta2 (RARbeta2) receptor agonist, with a pEC50 of 8.0[1].

IC50 & Target

RARβ2

8.0 (pEC50)

体外研究
(In Vitro)

AC-261066 exhibits good oral bioavailability in rats (F oral = 52%)[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

353.41

Formula

C17H20FNO4S
CAS 号

870773-76-5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Lund BW, et al. Discovery of a potent, orally available, and isoform-selective retinoic acid beta2 receptor agonist. J Med Chem. 2005 Dec 1;48(24):7517-9.

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