Thiol-PEG-COOH (MW 5000)

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Thiol-PEG-COOH (MW 5000) 

Thiol-PEG-COOH (MW 5000) 是一种 PROTAC linker,属于 PEG 类。Boc-NH-C6-amido-C4-acid 可用于合成 PROTAC 分子。

Thiol-PEG-COOH (MW 5000)

Thiol-PEG-COOH (MW 5000) Chemical Structure

规格 是否有货
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生物活性

Thiol-PEG-COOH (MW 5000) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

5000(Average)

Formula

C11H21NO5S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Targ. J Med Chem. 2019 Aug 21.

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