APN-C3-PEG4-alkyne

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APN-C3-PEG4-alkyne 

APN-C3-PEG4-alkyne 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

APN-C3-PEG4-alkyne

APN-C3-PEG4-alkyne Chemical Structure

CAS No. : 2183440-36-8

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生物活性

APN-C3-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

469.53

Formula

C25H31N3O6

CAS 号

2183440-36-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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