Fmoc-Lys (biotin-PEG4)-OH

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Fmoc-Lys (biotin-PEG4)-OH 

Fmoc-Lys (biotin-PEG4)-OH 是一种生物素标记的 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Fmoc-Lys (biotin-PEG4)-OH

Fmoc-Lys (biotin-PEG4)-OH Chemical Structure

CAS No. : 1334172-64-3

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生物活性

Fmoc-Lys (biotin-PEG4)-OH is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

842.01

Formula

C42H59N5O11S

CAS 号

1334172-64-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.

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