上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
Boc-11-aminoundecanoic acid
Boc-11-aminoundecanoic acid 是基于 Alkyl/ether 结构的 PROTAC linker, 可以用来制备 MS432 (HY-130602)。
Boc-11-aminoundecanoic acid Chemical Structure
CAS No. : 10436-25-6
规格 | 是否有货 | ||
---|---|---|---|
100 mg | 询价 | ||
250 mg | 询价 | ||
500 mg | 询价 |
* Please select Quantity before adding items.
生物活性 |
Boc-11-aminoundecanoic acid is an Alkyl/ether-based PROTAC linker can be used in the synthesis of MS432 (HY-130602)[1]. |
||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
IC50 & Target |
|
||||||||||||
体外研究 (In Vitro) |
MS432 is a first-in-class and highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
||||||||||||
分子量 |
301.42 |
||||||||||||
Formula |
C16H31NO4 |
||||||||||||
CAS 号 |
10436-25-6 |
||||||||||||
运输条件 |
Room temperature in continental US; may vary elsewhere. |
||||||||||||
储存方式 |
|
||||||||||||
参考文献 |
|
所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务