N-(Azido-PEG3)-N-Boc-PEG4-acid

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N-(Azido-PEG3)-N-Boc-PEG4-acid 

N-(Azido-PEG3)-N-Boc-PEG4-acid 是一种 PEGPROTAC linker, 含有一个叠氮基团,可以用来合成 PROTAC。

N-(Azido-PEG3)-N-Boc-PEG4-acid

N-(Azido-PEG3)-N-Boc-PEG4-acid Chemical Structure

CAS No. : 2112731-95-8

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生物活性

N-(Azido-PEG3)-N-Boc-PEG4-acid is a PEG-based PROTAC linker with a terminal azide group and is used in the synthesis of PROTACs[1]

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

566.64

Formula

C24H46N4O11

CAS 号

2112731-95-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Kanazaki K, et al. Feasibility of poly(ethylene glycol) derivatives as diagnostic drug carriers for tumor imaging. J Control Release. 2016 Mar 28;226:115-23.

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