N3-PEG8-CH2COOH

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N3-PEG8-CH2COOH 

N3-PEG8-CH2COOH 是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC。

N3-PEG8-CH2COOH

N3-PEG8-CH2COOH Chemical Structure

CAS No. : 1343472-07-0

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生物活性

N3-PEG8-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

453.48

Formula

C18H35N3O10

CAS 号

1343472-07-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Steinmetz NF, et al. Intravital imaging of human prostate cancer using viral nanoparticles targeted to gastrin-releasing Peptide receptors. Small. 2011 Jun 20;7(12):1664-72.

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