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Sodium aescinate (Synonyms: 七叶皂苷钠)
Sodium aescinate 是一种来源 Aesculus hippocastanum 种子的三萜皂苷,具有抗炎、抗氧化活性。Sodium aescinate 能通过靶向 CARMA3/NF-κB 途径,抑制抑制肝癌生长。
Sodium aescinate Chemical Structure
CAS No. : 20977-05-3
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5 mg | 询价 | ||
10 mg | 询价 | ||
25 mg | 询价 |
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生物活性 |
Sodium aescinate is a triterpene saponin derived from Aesculus hippocastanum seeds, with anti-inflammatory and antioxidant activities[1]. Sodium aescinate inhibits hepatocellular carcinoma growth by targeting CARMA3/NF-κB pathway[2]. |
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体外研究 (In Vitro) |
Sodium aescinate can block signals transiting to downstream molecules AKT, ERK, inhibit the proliferation of breast cancer cell MCF-7 cell apoptosis and induced cell apoptosis by suppressing the activation of SRC[3]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
体内研究 (In Vivo) |
Sodium aescinate may effectively controls and improves wound healing in diabetic rats via its anti-inflammatory and antioxidant activities[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
Clinical Trial |
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分子量 |
1123.21 |
Formula |
C54H83NaO23 |
CAS 号 |
20977-05-3 |
中文名称 |
七叶皂苷钠 |
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
参考文献 |
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