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DYRKs-IN-2
DYRKs-IN-2 (例132) 是一种有效的 DYRKs 抑制剂，对 DYRK1B 和 DYRK1A 的 IC50 分别为 9 nM 和 5 nM。DYRKs-IN-2 有抗肿瘤活性。
DYRKs-IN-2 Chemical Structure
CAS No. : 1386980-04-6
| 规格 | 是否有货 | ||
|---|---|---|---|
| 100 mg | 询价 | ||
| 250 mg | 询价 | ||
| 500 mg | 询价 |
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| 生物活性 |
DYRKs-IN-2 (Example 132) is a potent DYRKs inhibitor with IC50s of 30.6 nM and 12.8 nM for DYRK1B and DYRK1A, respectively. DYRKs-IN-2 has antitumor activity[1]. |
IC50 & Target |
IC50: 30.6 nM (DYRK1B) and 12.8 nM (DYRK1A)[2] |
|---|---|
| 体外研究 (In Vitro) |
DYRKs-IN-2 (Example 132) has an EC50 of 22.8 nM for SW620 cell line[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
| 分子量 |
632.16 |
| Formula |
C32H38ClN9O3 |
| CAS 号 |
1386980-04-6 |
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| 参考文献 |
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