Girentuximab(Synonyms: G250; cG250)

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Girentuximab (Synonyms: G250; cG250)

Girentuximab (G250) 是一种嵌合单克隆抗体,可与碳酸酐酶 IX (CAIX) 结合,碳酸酐酶 IX 是一种在透明细胞肾细胞癌 (ccRCC) 中广泛表达的细胞表面糖蛋白。

Girentuximab(Synonyms: G250;  cG250)

Girentuximab Chemical Structure

CAS No. : 916138-87-9

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生物活性

Girentuximab (G250) is a chimeric monoclonal antibody that binds carbonic anhydrase IX (CAIX), a cell surface glycoprotein ubiquitously expressed in clear cell renal cell carcinoma (ccRCC)[1].

体外研究
(In Vitro)

Girentuximab is an IgG1 κ light chain chimeric version of a murine monoclonal antibody (mAb) and recognizes the antigen CAIX[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

CAS 号

916138-87-9

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Chamie K, et al. Adjuvant Weekly Girentuximab Following Nephrectomy for High-Risk Renal Cell Carcinoma: The ARISER Randomized Clinical Trial. JAMA Oncol. 2017;3(7):913-920.

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