BCL6-IN-6

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

BCL6-IN-6 

BCL6-IN-6 是转录抑制 B 细胞淋巴瘤 6 (BCL6) 的有效抑制剂。BCL6-IN-6 显着阻断 BCL6 与其辅阻遏物的相互作用，并以剂量依赖性方式重新激活 BCL6 靶基因。BCL6-IN-6 具有研究弥漫性大B细胞淋巴瘤 (DLBCL) 的潜力。

BCL6-IN-6

BCL6-IN-6 Chemical Structure

CAS No. : 2408882-54-0

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生物活性

BCL6-IN-6 is a potent inhibitor of transcriptional repressor B-cell lymphoma 6 (BCL6). BCL6-IN-6 significantly blocks the interaction of BCL6 with its corepressors and reactivates BCL6 target genes in a dose-dependent manner. BCL6-IN-6 has the potential for the research of diffuse large B-cell lymphoma (DLBCL)[1].

IC50 & Target

BCL6[1]
分子量

522.64

Formula

C27H31FN6O2S
CAS 号

2408882-54-0
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Guo W, et al. Synthesis and Biological Evaluation of B-Cell Lymphoma 6 Inhibitors of N-Phenyl-4-pyrimidinamine Derivatives Bearing Potent Activities against Tumor Growth. J Med Chem. 2020;63(2):676-695.

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