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AUTAC2
AUTAC2 是一种 FKBP12 靶向自噬介导降解体 (AUTAC)。AUTAC2 包含一个 FBnG 和 SLF 部分，其中 SLF 与FKBP12 非共价结合。
AUTAC2 Chemical Structure
CAS No. : 2241669-08-7
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| 生物活性 |
AUTAC2 is a FKBP12-targeting autophagy-mediated degrader (AUTAC). AUTAC2 contains an FBnG (p-Fluorobenzyl Guanine) and an SLF (c ligand of FKBP) moiety. SLF binds non-covalently to FKBP12[1]. |
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| 体外研究 (In Vitro) |
AUTAC1 (1-100 μM, 24 h) silences endogenous FKBP12 in hela cells[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. Western Blot Analysis[1]
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| 分子量 |
1229.42 |
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| Formula |
C61H81FN10O14S |
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| CAS 号 |
2241669-08-7 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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| 参考文献 |
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