上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
DS-7423
DS-7423 是 PI3K 和 mTOR 的双抑制剂,其对 PI3Kα 和 mTOR 的IC50 值分别为15.6 nM 和 34.9 nM。DS-7423 具有抗癌活性。
DS-7423 Chemical Structure
CAS No. : 1222104-37-1
规格 | 价格 | 是否有货 | 数量 |
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5 mg | ¥4500 | In-stock | |
10 mg | ¥8000 | In-stock | |
25 mg | ¥16500 | In-stock | |
50 mg | ¥26000 | In-stock | |
100 mg | ¥40000 | In-stock | |
200 mg | 询价 | ||
500 mg | 询价 |
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DS-7423 相关产品
•相关化合物库:
- Clinical Compound Library Plus
- Bioactive Compound Library Plus
- Kinase Inhibitor Library
- PI3K/Akt/mTOR Compound Library
- Stem Cell Signaling Compound Library
- Anti-Cancer Compound Library
- Clinical Compound Library
- Autophagy Compound Library
- Anti-Aging Compound Library
- Antioxidants Compound Library
- Differentiation Inducing Compound Library
- Reprogramming Compound Library
- Oxygen Sensing Compound Library
- Glycolysis Compound Library
- Cytoskeleton Compound Library
- Anti-Breast Cancer Compound Library
- Anti-Lung Cancer Compound Library
- Anti-Pancreatic Cancer Compound Library
- Anti-Blood Cancer Compound Library
- Anti-Cancer Metabolism Compound Library
- Angiogenesis Related Compound Library
- Glucose Metabolism Compound Library
- Anti-Liver Cancer Compound Library
- Anti-Colorectal Cancer Compound Library
生物活性 |
DS-7423 is a dual PI3K and mTOR inhibitor, with IC50 values of 15.6 nM, 34.9 nM for PI3Kα and mTOR, respectively. DS-7423 possesses anti-tumor activity[1][2]. |
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体外研究 (In Vitro) |
DS-7423 increases TP53 expression, the level of p-TP53 on Ser-46, and induced apoptosisrelated TP53 target genes (TP53AIP1 and PUMA) in OCCC cells[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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Clinical Trial |
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分子量 |
520.51 |
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Formula |
C22H27F3N10O2 |
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CAS 号 |
1222104-37-1 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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参考文献 |
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