Fludarabine triphosphate(Synonyms: F-ara-ATP)

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Fludarabine triphosphate (Synonyms: F-ara-ATP)

Fludarabine triphosphate (F-ara-ATP) 是Fludarabine phosphate (HY-B0028) 的细胞毒性代谢物，抑制核糖核苷酸还原酶和 DNA 聚合酶，最终导致细胞凋亡。

Fludarabine triphosphate(Synonyms: F-ara-ATP)

Fludarabine triphosphate Chemical Structure

CAS No. : 74832-57-8

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生物活性

Fludarabine triphosphate (F-ara-ATP), the cytotoxic metabolite of Fludarabine phosphate (HY-B0028), inhibits ribonucleotide reductase and DNA polymerase and ultimately leads to cellular apoptosis[1].

分子量

525.17

Formula

C10H15FN5O13P3
CAS 号

74832-57-8
中文名称

三磷酸氟达拉滨
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Erica L. Woodahl, et al. A NOVEL PHENOTYPIC METHOD TO DETERMINE FLUDARABINE TRIPHOSPHATE ACCUMULATION IN T-LYMPHOCYTES FROM HEMATOPOIETIC CELL TRANSPLANTATION PATIENTS. J Cell Mol Med. 2020 Jul 31.

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