上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。
D-3263
D-3263 是一种有效的 TRPM8 激动剂，具有抗肿瘤活性。
D-3263 Chemical Structure
CAS No. : 947257-66-1
| 规格 | 是否有货 | ||
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| 100 mg | 询价 | ||
| 250 mg | 询价 | ||
| 500 mg | 询价 |
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D-3263 的其他形式现货产品:
| 生物活性 |
D-3263 is an agonist of transient receptor potential melastatin member 8 (TRPM8) with potential antineoplastic activity. |
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| 体外研究 (In Vitro) |
D-3263 induces calcium flux and cell death in in vitro cells expressing TRPM8[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
| 体内研究 (In Vivo) |
D-3263 (50 or 100 mg/kg/d) alone or with Finasteride (10 mg/kg/d) results in reduction in prostate hyperplasia of rats with evidence of a dose response. The highest dose of the TRPM8 agonist D-3263, given in combination with Finasteride, results in lower prostate weights than the highest dose of D-3263 or Finasteride given alone, suggesting a potential additive effect[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
| Clinical Trial |
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| 分子量 |
373.49 |
| Formula |
C21H31N3O3 |
| CAS 号 |
947257-66-1 |
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| 参考文献 |
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