上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。
DC44SMe
DC44SMe 是 DNA 烷化剂的磷酸盐前体，可用于合成抗体偶联药物 (ADC)。DC44SMe 对 Ramos，Namalwa 和 HL60/s 癌细胞的 IC50 值分别为 2.0 nM, 2.8 nM, 和 1.9 nM。DC44SMe 可用于靶向癌症研究。
DC44SMe Chemical Structure
CAS No. : 1354787-76-0
| 规格 | 是否有货 | ||
|---|---|---|---|
| 100 mg | 询价 | ||
| 250 mg | 询价 | ||
| 500 mg | 询价 |
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| 生物活性 |
DC44SMe, a phosphate prodrug of cytotoxic DNA alkylator DC44, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC44SMe exhibits IC50s of 2.0 nM, 2.8 nM, and 1.9 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC44SMe can be used for the targeted treatment of cancer[1]. |
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| 体外研究 (In Vitro) |
The phosphate prodrug may be a suitable choice for ADCs of effector molecules that do not possess sufficient water solubility or stability[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
| 分子量 |
806.29 |
| Formula |
C38H37ClN5O7PS2 |
| CAS 号 |
1354787-76-0 |
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| 参考文献 |
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