KRAS G12C inhibitor 17

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KRAS G12C inhibitor 17 

KRAS G12C inhibitor 17 是一种有效的 KRAS G12C 抑制剂,IC50 为 5 nM,详细信息请参考专利文献 WO2019110751A1 中的化合物 82。

KRAS G12C inhibitor 17

KRAS G12C inhibitor 17 Chemical Structure

CAS No. : 2349393-04-8

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生物活性

KRAS G12C inhibitor 17 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 82, has an IC50 of 5 nM[1].

IC50 & Target[1]

KRas G12C

5 nM (IC50)

分子量

471.88

Formula

C24H20ClF2N3O3

CAS 号

2349393-04-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Jason Grant Kettle, et al. Tetracyclic compounds as inhibitors of g12c mutant ras protein, for use as anti-cancer agents. WO2019110751A1.

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