4,4-Dimethyl-2-cyclopenten-1-one(Synonyms: 4,4-Dimethylcyclopent-2-enone)

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4,4-Dimethyl-2-cyclopenten-1-one (Synonyms: 4,4-Dimethylcyclopent-2-enone)

4,4-Dimethyl-2-cyclopenten-1-one 是可来源于 Apocyniveneti Folium 的天然产物,对不同肿瘤细胞显示出高选择性的细胞毒性。

4,4-Dimethyl-2-cyclopenten-1-one(Synonyms: 4,4-Dimethylcyclopent-2-enone)

4,4-Dimethyl-2-cyclopenten-1-one Chemical Structure

CAS No. : 22748-16-9

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生物活性

4,4-Dimethyl-2-cyclopenten-1-one, a natural compound from Apocyniveneti Folium, displays higher tumor-specific cytotoxicity[1].

体外研究
(In Vitro)

4,4-Dimethyl-2-cyclopenten-1-one selectively kills the tumor cells (HSC-2, HL-60). 4,4-Dimethyl-2-cyclopenten-1-one exhibits CC50 (50% cytotoxic concentration) values of 43.8 μg/mL, 152 μg/mL, 118 μg/mL, 14.0 μg/mL, 177 μg/mL and 123 μg/mL in HSC-2, HSC-3, HSG, HL-60, HGF and normal cells (HPC), respectively[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

110.15

Formula

C7H10O

CAS 号

22748-16-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Tohru Nakayachi, et al. Structure-activity relationships of alpha, beta-unsaturated ketones as assessed by their cytotoxicity against oral tumor cells. Anticancer Res. Mar-Apr 2004;24(2B):737-42.

    [2]. Wei-WeiZhu, et al. Cornstalk liquefaction in methanol/water mixed solvents. Fuel Processing Technology Volume 117, January 2014, Pages 1-7.

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