Altretamine hydrochloride(Synonyms: ENT-50852 hydrochloride; RB-1515 hydrochloride; WR-95704 hydrochloride)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Altretamine hydrochloride (Synonyms: ENT-50852 hydrochloride; RB-1515 hydrochloride; WR-95704 hydrochloride)

Altretamine hydrochloride 是一种烷化剂 (alkylator)，具有抗肿瘤活性。

Altretamine hydrochloride(Synonyms: ENT-50852 hydrochloride; RB-1515 hydrochloride; WR-95704 hydrochloride)

Altretamine hydrochloride Chemical Structure

CAS No. : 2975-00-0

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

Altretamine hydrochloride 的其他形式现货产品:

Altretamine

生物活性

Altretamine hydrochloride is an alkylating antineoplastic agent.

体外研究
(In Vitro)

Altretamine hydrochloride is an antineoplastic agent[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究
(In Vivo)

Altretamine (100, 133 mg/kg, ip.) in combination with Irofulven, increases the antitumor effect in mice bearing MV522 cells[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial

分子量

246.74

Formula

C9H19ClN6
CAS 号

2975-00-0
中文名称

盐酸六甲蜜胺
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Kelner MJ, et al. Synergy of irofulven in combination with other DNA damaging agents: synergistic interaction with altretamine, alkylating, and platinum-derived agents in the MV522 lung tumor model. Cancer Chemother Pharmacol. 2008 Dec;63(1):19-26.
Animal Administration
[1]

Mice[1]
Balb/c nu/nu 4 week old female mice weighing 18-22 g, receive s.c. injections of 8-10 million MV522 cells. Altretamine is administered i.p. three times a week for 3 weeks, starting on day 10 after tumor implantation. Tumor size is measured in two perpendicular diameters and tumor weight (TW) estimated according to the formula: w = [(width)2 × length/2]. Altretamine is prepared as stock solutions of 1-10 mg/mL in 40% DMSO/normal saline and diluted with 10% DMSO/normal saline as required[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献

  • [1]. Kelner MJ, et al. Synergy of irofulven in combination with other DNA damaging agents: synergistic interaction with altretamine, alkylating, and platinum-derived agents in the MV522 lung tumor model. Cancer Chemother Pharmacol. 2008 Dec;63(1):19-26.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务