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Kongensin A 纯度: ≥98.0%
Kongensin A 是一种从 Croton kongensis 中分离的天然产物。 Kongensin A 是一种有效的,共价的 HSP90 抑制剂,可阻断 RIP3 依赖性坏死病。Kongensin A 是一种有效的坏死性抑制剂和凋亡诱导剂,并具有潜在的抗坏死性和消炎性应用。
Kongensin A Chemical Structure
CAS No. : 885315-96-8
规格 | 价格 | 是否有货 | 数量 |
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1 mg | ¥9500 | In-stock | |
5 mg | ¥20800 | In-stock | |
10 mg | 询价 | ||
50 mg | 询价 |
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Kongensin A 相关产品
•相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
- Macrocyclic Compound Library
生物活性 |
Kongensin A is a natural product isolated from Croton kongensis. Kongensin A is an effective, covalent HSP90 inhibitor that blocks RIP3-dependent necroptosishas. Kongensin A is a potent necroptosis inhibitor and an apoptosis inducer. Kongensin A has potential anti-necroptosis and anti-inflammation applications[1]. |
IC50 & Target |
HSP90[1] |
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体外研究 (In Vitro) |
Kongensin A (0-15 μM; 6 hours; HT29 cells) treatment induces caspase activation and apoptosis in multiple cancer cell lines in a dosage-dependent manner[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. Apoptosis Analysis[1]
Western Blot Analysis[1]
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分子量 |
374.47 |
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Formula |
C22H30O5 |
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CAS 号 |
885315-96-8 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
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参考文献 |
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