Monascin(Synonyms: 红曲)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Monascin (Synonyms: 红曲) 纯度: 98.93%

Monascin 是可从红曲米中提取得到的一种氮杂类色素,有口服活性,具有抗肿瘤和抗炎活性。Monascin 还能抑制NOR 的激活。

Monascin(Synonyms: 红曲)

Monascin Chemical Structure

CAS No. : 21516-68-7

规格 价格 是否有货 数量
5 mg ¥16500 In-stock
10 mg   询价  
50 mg   询价  

* Please select Quantity before adding items.

Monascin 相关产品

相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus

生物活性

Monascin is a kind of azaphilonoid pigments extracted from Monascus pilosus-fermented rice (red-mold rice). Monascin also exhibits anti-tumor-initiating activity and anti-inflammatory activity with oral administration. Monascin inhibits the activation of NOR 1 (an NO donor)[1][2].

体内研究
(In Vivo)

Monascin (0.0025% in drinking water; mice) appears effective for the inhibition of UVB-initiated carcinogenesis on mouse skin[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: SENCAR mouse using a UVB irradiation as an initiator and TPA as a promoter[1].
Dosage: 0.0025% in drinking water.
Administration: Orally daily for 2 weeks in drinking water.
Result: Reduced the number of the papillomas.

分子量

358.43

Formula

C21H26O5

CAS 号

21516-68-7

中文名称

红曲

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. Akihisa T, et al. Anti-tumor-initiating effects of monascin, an azaphilonoid pigment from the extract of Monascus pilosus fermented rice (red-mold rice). Chem Biodivers. 2005 Oct;2(10):1305-9.

    [2]. Lee CL, et al. Monascus fermentation of dioscorea for increasing the production of cholesterol-lowering agent–monacolin K and antiinflammation agent–monascin. Appl Microbiol Biotechnol. 2006 Oct;72(6):1254-62.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务