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G3-C12
G3-C12 是 galectin-3 结合肽，Kd 值为 88 nM，具有抗肿瘤活性。
G3-C12 Chemical Structure
CAS No. : 848301-94-0
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G3-C12 的其他形式现货产品:
| 生物活性 |
G3-C12 is a galectin-3 binding peptide, with Kd of 88 nM, and shows anticancer activity. |
IC50 & Target |
Kd: 88 nM (Galectin-3)[1] |
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| 体外研究 (In Vitro) |
G3-C12 is a galectin-3 binding peptide, with high affinity (Kd) of 88 nM, but shows no affinity for other galectin family members or to other lectins. G3-C12 bearing opolymers N-(2-hydroxypropyl)methacrylamide (HPMA) potently and selectively targets colorectal cancer (CRC) tumour cells over-expressing galectin-3 and displays superior targetability to galectin-3 compared to the galactose bearing copolymer[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
1758.98 |
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| Formula |
C74H115N23O23S2 |
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| CAS 号 |
848301-94-0 |
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| Sequence |
Ala-Asn-Thr-Pro-Cys-Gly-Pro-Tyr-Thr-His-Asp-Cys-Pro-Val-Lys-Arg |
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| Sequence Shortening |
ANTPCGPYTHDCPVKR |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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| 参考文献 |
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