Sildenafil-d3(Synonyms: UK-92480-d3)

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Sildenafil-d3 (Synonyms: UK-92480-d3) 纯度: 99.99%

Sildenafil-d3 是氘标记的西地那非。Sildenafil (UK-92480) 是一种有效的磷酸二酯酶 5 (PDE5) 抑制剂，IC50 为 5.22 nM。

Sildenafil-d3(Synonyms: UK-92480-d3)

Sildenafil-d3 Chemical Structure

CAS No. : 1126745-90-1

规格 价格 是否有货 数量
1 mg ￥1900 In-stock
5 mg ￥4600 In-stock
10 mg ￥7000 In-stock
50 mg   询价  
100 mg   询价  

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生物活性

Sildenafil-d3 is deuterium labeled Sildenafil-d3. Sildenafil (UK-92480) is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM.

分子量

477.59

Formula

C22H27D3N6O4S
CAS 号

1126745-90-1
中文名称

西地那非 d3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
参考文献

  • [1]. Wang Z, et al. The Selectivity and Potency of the New PDE5 Inhibitor TPN729MA. J Sex Med. 2013 Nov;10(11):2790-7

    [2]. [2].Li BB, et al. Sildenafil potentiates the proliferative effect of porcine pulmonary artery smooth muscle cells induced by serotonin in vitro. Chin Med J (Engl). 2011 Sep;124(17):2733-40.

    [3]. [3]. Moretti R, et al. Sildenafil, a cyclic GMP phosphodiesterase inhibitor, induces microglial modulation after focal ischemia in the neonatal mouse brain. J Neuroinflammation. 2016 Apr 28;13(1):95.

    [4]. Korkmaz MF, et al. The Effect of Sildenafil on Recuperation from Sciatic Nerve Injury in Rats. Balkan Med J. 2016 Mar;33(2):204-11.

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