Umbelliferone-d5(Synonyms: 7-Hydroxycoumarin-d5; Hydrangin-d5; NSC 19790-d5)

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Umbelliferone-d5 (Synonyms: 7-Hydroxycoumarin-d5; Hydrangin-d5; NSC 19790-d5)

Umbelliferone-d5 (7-Hydroxycoumarin-d5) 是 Umbelliferone 的氘代物。Umbelliferone (7-Hydroxycoumarin) 是香豆素家族的天然产物，是一种荧光化合物，可用作防晒剂。

Umbelliferone-d5(Synonyms: 7-Hydroxycoumarin-d5; Hydrangin-d5; NSC 19790-d5)

Umbelliferone-d5 Chemical Structure

CAS No. : 1215373-23-1

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生物活性

Umbelliferone-d5 (7-Hydroxycoumarin-d5) is the deuterium labeled Umbelliferone. Umbelliferone (7-Hydroxycoumarin), a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

167.17

Formula

C9HD5O3
CAS 号

1215373-23-1
中文名称

7-羟基香豆素 d5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Yu SM, et al. Umbelliferone exhibits anticancer activity via the induction of apoptosis and cell cycle arrest in HepG2 hepatocellular carcinoma cells. Mol Med Rep. 2015 Sep;12(3):3869-3873.

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